C Met Antibody Cell Signaling

Wild type hap1 whole cell lysate lane 2.

C met antibody cell signaling.

Anti met c met antibody epr19067 ab216574 at 1 1000 dilution lane 1. Zero bias scores article reviews protocol conditions and more. C met also called tyrosine protein kinase met or hepatocyte growth factor receptor hgfr is a protein that in humans is encoded by the met gene the protein possesses tyrosine kinase activity. Met knockout hap1 whole cell lysate lysates proteins at 40 µg per lane.

Green ab216574 observed at 155 kda. The cells were labeled c met 3d4 mouse monoclonal antibody 187366 at 1 250 dilution in0 1 bsa and incubated for 3 hours at room temperature and then labeled with goat anti mouse igg h l superclonal secondary antibody alexa fluor 488 conjugate product a28175 at a dilution of 1 2000 for 45 minutes at room temperature panel a. Ab74217 has been referenced in 9 publications. Red loading control ab18058 observed at 130 kda.

Oncol rep 41 1497 1508 2019. Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3. Yin l et al. In order to learn how oncogene addiction can be broken in tumors with met amplification by the anti c met monoclonal antibody abt 700 cell signaling technology c met antibody cell signaling 3077 was used in immunohistochemistry paraffin section on human samples fig 3 and in western blot on human samples fig 1.

Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3. 155 kda lanes 1 2. Interaction of met with hgf results in autophosphorylation at multiple tyrosines which recruit several downstream signaling components including gab1 c cbl and pi3 kinase 3. Anti c met supplied by cell signaling technology inc used in various techniques.

Microrna 200a suppresses migration and invasion and enhances the radiosensitivity of nsclc cells by inhibiting the hgf c met signaling pathway. These fundamental events are important for all of the biological functions involving met kinase activity. 99 100 based on 5 pubmed citations. These fundamental events are important for all of the biological functions involving met kinase activity.

Merged signal red and green. Du m et al. These fundamental events are important for all of the biological functions involving met kinase activity. Ligand binding at the cell surface induces autophosphorylation of met that provides docking sites for downstream signaling molecules.

It is linked to functions such as cell proliferation scattering morphogenesis and survival.